Opsini su članovi familije G protein-spregnutih receptora. Osim vizuelnih opsina, sisari poseduje nekoliko fotoreceptivnih ne-vizuelnih opsina koji su izraženi u tkivima izvan oka. Gen opsina-3 je u znatnoj meri izražen u mozgu i testisima, a u maloj meri i u jetri, materici, srcu, plućima, skeletalnim mišima, bubrezima, i pankreasu. Ovaj gene isto tako može da bude izražen u mrežnjači. Ovaj protein poseduje kanoničke osobine fotoreceptivnih opsina.[3]
Literatura
↑Blackshaw S, Snyder SH (Jun 1999). „Encephalopsin: a novel mammalian extraretinal opsin discretely localized in the brain”. J Neurosci19 (10): 3681–90. PMID10234000.
↑Halford S, Freedman MS, Bellingham J, Inglis SL, Poopalasundaram S, Soni BG, Foster RG, Hunt DM (Jun 2001). „Characterization of a novel human opsin gene with wide tissue expression and identification of embedded and flanking genes on chromosome 1q43”. Genomics72 (2): 203–8. DOI:10.1006/geno.2001.6469. PMID11401433.
Bonaldo MF, Lennon G, Soares MB (1997). „Normalization and subtraction: two approaches to facilitate gene discovery.”. Genome Res.6 (9): 791–806. DOI:10.1101/gr.6.9.791. PMID8889548.
Halford S, Bellingham J, Ocaka L i dr.. (2002). „Assignment of panopsin (OPN3) to human chromosome band 1q43 by in situ hybridization and somatic cell hybrids.”. Cytogenet. Cell Genet.95 (3-4): 234–5. DOI:10.1159/000059351. PMID12063405.
Kasper G, Taudien S, Staub E i dr.. (2003). „Different structural organization of the encephalopsin gene in man and mouse.”. Gene295 (1): 27–32. DOI:10.1016/S0378-1119(02)00799-0. PMID12242008.
Alam NA, Gorman P, Jaeger EE i dr.. (2004). „Germline deletions of EXO1 do not cause colorectal tumors and lesions which are null for EXO1 do not have microsatellite instability.”. Cancer Genet. Cytogenet.147 (2): 121–7. DOI:10.1016/S0165-4608(03)00196-1. PMID14623461.
Gregory SG, Barlow KF, McLay KE i dr.. (2006). „The DNA sequence and biological annotation of human chromosome 1.”. Nature441 (7091): 315–21. DOI:10.1038/nature04727. PMID16710414.
