GPR15

G protein-spregnuti receptor 15
Identifikatori
Simboli	GPR15; MGC126828; MGC126830
Vanjski ID	OMIM: 601166 MGI: 1918473 HomoloGene: 3869 IUPHAR: GPR15 GeneCards: GPR15 Gene
Ontologija gena
Molekularna funkcija	• aktivnost rodopsinu-sličnog receptora • receptorska aktivnost • aktivnost purinergičkog nukleotidnog receptora, G-protein spregnutog
Celularna komponenta	• integralno sa ćelijskom membranom • membrana
Biološki proces	• prenos signala • signalni put G-protein spregnutog receptora
Pregled RNK izražavanja
	podaci
Ortolozi

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GPR15, G-protein spregnuti receptor 15, je protein koji je kod čoveka kodiran GPR15 genom.^[1]^[2]

Literatura

↑ Heiber M, Marchese A, Nguyen T, Heng HH, George SR, O'Dowd BF (Feb 1997). „A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3”. Genomics 32 (3): 462–5. DOI:10.1006/geno.1996.0143. PMID 8838812.
↑ „Entrez Gene: GPR15 G protein-coupled receptor 15”.

Dodatna literatura

Cunningham AL, Li S, Juarez J, et al. (2000). „The level of HIV infection of macrophages is determined by interaction of viral and host cell genotypes.”. J. Leukoc. Biol. 68 (3): 311–7. PMID 10985245.
Deng HK, Unutmaz D, KewalRamani VN, Littman DR (1997). „Expression cloning of new receptors used by simian and human immunodeficiency viruses.”. Nature 388 (6639): 296–300. DOI:10.1038/40894. PMID 9230441.
Farzan M, Choe H, Martin K, et al. (1997). „Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection.”. J. Exp. Med. 186 (3): 405–11. DOI:10.1084/jem.186.3.405. PMC 2198994. PMID 9236192.
Clayton F, Kotler DP, Kuwada SK, et al. (2001). „Gp120-induced Bob/GPR15 activation: a possible cause of human immunodeficiency virus enteropathy.”. Am. J. Pathol. 159 (5): 1933–9. PMC 1867054. PMID 11696454.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Croitoru-Lamoury J, Guillemin GJ, Boussin FD, et al. (2003). „Expression of chemokines and their receptors in human and simian astrocytes: evidence for a central role of TNF alpha and IFN gamma in CXCR4 and CCR5 modulation.”. Glia 41 (4): 354–70. DOI:10.1002/glia.10181. PMID 12555203.
Maresca M, Mahfoud R, Garmy N, et al. (2003). „The virotoxin model of HIV-1 enteropathy: involvement of GPR15/Bob and galactosylceramide in the cytopathic effects induced by HIV-1 gp120 in the HT-29-D4 intestinal cell line.”. J. Biomed. Sci. 10 (1): 156–66. DOI:10.1159/000068089. PMID 12566994.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Blaak H, Boers PH, Gruters RA, et al. (2005). „CCR5, GPR15, and CXCR6 are major coreceptors of human immunodeficiency virus type 2 variants isolated from individuals with and without plasma viremia.”. J. Virol. 79 (3): 1686–700. DOI:10.1128/JVI.79.3.1686-1700.2005. PMC 544080. PMID 15650194.
Cilliers T, Willey S, Sullivan WM, et al. (2005). „Use of alternate coreceptors on primary cells by two HIV-1 isolates.”. Virology 339 (1): 136–44. DOI:10.1016/j.virol.2005.05.027. PMID 15992849.

[pmid8838812-1] Heiber M, Marchese A, Nguyen T, Heng HH, George SR, O'Dowd BF (Feb 1997). „A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3”. Genomics 32 (3): 462–5. DOI:10.1006/geno.1996.0143. PMID 8838812.

[entrez-2] „Entrez Gene: GPR15 G protein-coupled receptor 15”.

[1]

[2]

GPR15

Literatura

Dodatna literatura

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