The midfielder became a regular starter for Vélez during the 2017–18 Argentine Primera División. Due to his strong performances, at the end of the first semester of the season Cáseres was linked with a possible move to Atlético Madrid, reportedly willing to pay his buyout clause of US$12 million.[1][2]
Villarreal
Cáseres signed a five-year contract with Villarreal CF on 16 July 2018.[3]
Club América
On 29 January 2020, Cáseres joined Liga MX side Club América on a one-year loan agreement up to December 31, 2020, with the option for a permanent deal.[4]
Vélez Sarfield
On 22 February 2021, Cáseres returned to Argentina to Primera División side Vélez Sarfield, on a loan deal until December 2021. After that, in 2022 Cáseres signed a contract with Vélez Sarfield until December 2024 for $2.36 Million.[5][6]