The 1921–22 Lancashire Cup competition, the fourteenth contest for this regional rugby league competition, saw a new name on the trophy, Warrington. They beat Oldham in the final at The Cliff, Broughton, Salford by a score of 7–5. The final was watched by 18,000 and receipts were £1,200.
Background
The number of teams entering this year's competition remained at the previous level of 14, this enabled the competition to be run with only 2 byes in the first round.