Selenium responsive proteins This article needs to be updated. Please help update this article to reflect recent events or newly available information. (November 2021) Selenium responsive proteins within human biology, are the class of proteins sensitive to selenium, in healthy human beings, in cancer patients, in in-vivo models or in-vitro cell culture models. The original gi accession (version) numbers have been updated to NCBI accession number and protein names updated accordingly.[clarification needed] Accession Number Common abbreviation Protein name Responsive in Selenium compound technique used source Q08091 CNN1 Calponin-1 TRAMP (prostate cancer mouse model) MSeC iTRAQ LC-MS/MS Zhang 2010 [1] NP_035656 TAGLN Transgelin TRAMP (prostate cancer mouse model) MSeC iTRAQ LC-MS/MS Zhang 2010 [1] NP_033822 APOA1 Apolipoprotein A-I TRAMP (prostate cancer mouse model) MSeC, MseA iTRAQ LC-MS/MS Zhang 2010 [1] NP_038499 ANXA4 Annexin A4 TRAMP (prostate cancer mouse model) MseA iTRAQ LC-MS/MS Zhang 2010 [1] gi21071030 A1BG Alpha 1B-glycoprotein Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2] gi4557871 TF Transferrin Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2] gi4502501 C4b Complement component 4B proprotein Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2] NP_059086 SEMG1 semenogelin I TRAMP DLP UP MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1] CAA47699 BGPG Biliary glycoprotein TRAMP DLP UP MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1] NP_780375 BASP1 brain acid soluble protein 1 TRAMP DLP UP MSeA iTRAQ LC-MS/MS Zhang 2010 [1] NP_031789 Cysteine-rich protein 1 TRAMP DLP UP MSeA iTRAQ LC-MS/MS Zhang 2010 [1] NP_059067 HPX Hemopexin TRAMP DLP UP MSeA iTRAQ LC-MS/MS Zhang 2010 [1] gi7305531 Seminal vesicle secretion 6 TRAMP DLP UP MSeA iTRAQ LC-MS/MS Zhang 2010 [1] NP_780375 DMBTL_MOUSE putative DMBT1-like protein precursor TRAMP DLP UP MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi6755212 Proteasome (prosome, macropain) 28 subunit, α TRAMP DLP UP MSeC iTRAQ LC-MS/MS Zhang 2010 [1] NP_035309 PSAP Prosaposin TRAMP DLP UP MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi123794006 FUSE-binding protein 2 TRAMP DLP UP MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi84875537 Nucleolin TRAMP DLP UP MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi40254525 Tropomyosin 3, gamma TRAMP DLP UP MSeC iTRAQ LC-MS/MS Zhang 2010 [1] NP_032775 NUCB1 Nucleobindin 1 TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi94717635 Progesterone receptor membrane component TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi21704156 Caldesmon 1 TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi31980648 ATP synthase, H+ transporting mitochondrial F1 complex β TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi10946574 Creatine kinase, brain TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi94367355 Similar to 60S ribosomal protein L5 TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi31981520 Pancreatic ribonuclease TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi6754084 Glutathione S-transferase, mu 1 TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi6680121 Glutathione S-transferase, μ 2 TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi31981302 Annexin A6 TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi6678740 Lumican TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi94403723 Similar to Heat shock 70-kDa protein 1B (HSP70.1) TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi89574165 Succinate dehydrogenase complex subunit A TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1] gi70778915 Moesin TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1] gi6679567 Polymerase I and transcript release factor TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1] gi31791059 Activated leukocyte cell adhesion molecule TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1] gi76779293 Keratin 8 TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1] gi6671549 Peroxiredoxin 6 TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1] gi6680836 Calreticulin TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1] NP_808579 TGM4 protein-glutamine gamma-glutamyltransferase 4 TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1] gi8567372 Probasin TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1] gi2506545 78-kDa glucose-regulated protein precursor (GRP 78) TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1] gi7643979 170-kDa glucose regulated protein GRP170 TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1] gi31542563 DnaJ (Hsp40) homolog, subfamily C, member 3 TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1] gi71774133 Peptidylprolyl isomerase B (PPI) TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1] gi130232 Protein disulfide isomerase b family, ERp57 subfamily TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1] gi129729 Protein disulfide isomerase ERp59 TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1] gi86198316 Protein disulfide isomerase associated 4 TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1] gi58037267 Protein disulfide isomerase-associated 6 TRAMP DLP DOWN MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi6753010 Anterior gradient 2 TRAMP DLP DOWN MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi42794267 Experimental autoimmune prostatitis antigen 2 TRAMP DLP DOWN MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi31543942 Vinculin TRAMP DLP DOWN MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi94387119 PREDICTED: similar to heat shock protein 8 TRAMP DLP DOWN MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi6752952 Actin, γ2, smooth muscle, enteric TRAMP DLP DOWN MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi94381948 PREDICTED: similar to Fc fragment of IgG binding protein TRAMP DLP DOWN MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi6754482 Keratin complex 1, acidic, gene 18 TRAMP DLP DOWN MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1] gi5031777 isocitrate dehydrogenase Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2] NP_005134 HP Haptoglobin isoform 1 preproprotein Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2] gi42716297 CLU Clusterin isoform 1 Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2] gi17318569 Keratin 1 Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2] gi4507725 Transthyretin Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2] gi21361198 AAT Alpha-1 antitrypsin Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2] gi4557287 Angiotensin precursor Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2] gi4502027 Albumin precursor Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2] References ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq ar as at au av aw ax ay az Zhang, J.; Wang, L.; Anderson, L. B.; Witthuhn, B.; Xu, Y.; Lu, J. (2010). "Proteomic Profiling of Potential Molecular Targets of Methyl-Selenium Compounds in the Transgenic Adenocarcinoma of Mouse Prostate Model". Cancer Prevention Research. 3 (8): 994–1006. doi:10.1158/1940-6207.CAPR-09-0261. PMID 20647336. ^ a b c d e f g h i j k Sinha, R.; Sinha, I.; Facompre, N.; Russell, S.; Somiari, R.; Richie Jr, J.; El-Bayoumy, K. (2010). "Selenium responsive proteins in sera of selenium-enriched yeast supplemented healthy African American and Caucasian men". Cancer Epidemiology, Biomarkers & Prevention. 19 (9): 2332–2340. doi:10.1158/1055-9965.EPI-10-0253. PMC 3326597. PMID 20643827.

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