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Formaldehid transketolaza

Formaldehid transketolaza
Identifikatori
EC broj 2.2.1.3
CAS broj 124566-23-0
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Formaldehid transketolaza (EC 2.2.1.3, dihidroksiacetonska sintaza) je enzim sa sistematskim imenom D-ksiluloza-5-fosfat:formaldehid glikolaldehidtransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

D-ksiluloza 5-fosfat + formaldehid gliceraldehid 3-fosfat + gliceron

Ovaj enzim je tiamin-difosfatni protein. On nije identical sa EC 2.2.1.1, transketolazom. Ovaj enzim takođe konvertuje hidroksipiruvat i formaldehid u gliceron i CO2.

Reference

  1. Bystrykh, L.V., Sokolov, A.P. and Trotsenko, Yu.A. (1981). „Separation of transketolase and dihydroxyacetone synthase from methylotrophic yeasts”. Dokl. Akad. Nauk SSSR. 258: 499-501. PMID 7249920. 
  2. Kato, N., Higuchi, T., Sakazawa, C., Nishizawa, T., Tani, Y. and Yamada, H. (1982). „Purification and properties of a transketolase responsible for formaldehyde fixation in a methanol-utilizing yeast, Candida boidinii (Kloeckera sp.) No. 2201”. Biochim. Biophys. Acta 715: 143-150. PMID 7074134. 
  3. Waites, M.J. and Quayle, J.R. (1981). „The interrelation between transketolase and dihydroxyacetone synthase activities in the methylotrophic yeast Candida boidinii”. J. Gen. Microbiol. 124: 309-316. PMID 6276498. 

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