Born in Brescia, Panada started playing football at grassroots level in the nearby comune of Torbole Casaglia: in 2008, aged six, he trialed for his hometown club before joining the youth sector of Brescia's main rivals, Atalanta.[1] He eventually came through all the youth ranks of the club until the under-19 team, with whom he won a national championship and a Super Cup and took part in the UEFA Youth League.[1] In the meantime, the midfielder also received several call-ups to the first team, albeit without making his senior debut in any of those occasions.[2]
On 7 July 2022, Panada joined Serie B club Modena on a season-long loan.[3] He subsequently made his professional debut on 31 July, coming in as a substitute in the second half of a 3–1 win against Catanzaro, in the preliminary turn of the Coppa Italia.[4] He then started the following cup match on 8 August, as his side gained a 3–2 home win against Sassuolo.[5] Finally, on 14 August, he made his league debut, coming in as a substitute in the second half of a 1–0 loss against Frosinone.[6]
On 27 July 2023, Panada signed a four-year deal for Sampdoria. The transfer is structured as an initial loan for the 2023–24 season with an option to make the transfer permanent after, with Atalanta retaining a counter-option to buy his rights back at that time.[7]
Panada is a defensive midfielder, who can also play in a more advanced position, or even as a central defender.[1] Despite having a slightly diminutive physique, he still can win the ball back and defend it from opponents, thanks to his strength and technique. A right-footed player, he is also regarded for his passing, his ability to dictate the team's tempo and his shooting.[1][14]