Protein-coding gene in the species Homo sapiens
Group 10 secretory phospholipase A2 is an enzyme that in humans is encoded by the PLA2G10 gene .[ 5] [ 6]
See also
References
^ a b c ENSG00000069764 GRCh38: Ensembl release 89: ENSG00000276870, ENSG00000069764 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022683 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Cupillard L, Koumanov K, Mattei MG, Lazdunski M, Lambeau G (Jul 1997). "Cloning, chromosomal mapping, and expression of a novel human secretory phospholipase A2" . J Biol Chem . 272 (25): 15745– 52. doi :10.1074/jbc.272.25.15745 PMID 9188469 . ^ "Entrez Gene: PLA2G10 phospholipase A2, group X" .
Further reading
Schröder HC, Perovic S, Kavsan V, et al. (1998). "Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death". Neurotoxicology . 19 (4– 5): 683– 8. PMID 9745929 . Sartipy P, Camejo G, Svensson L, Hurt-Camejo E (2002). "Phospholipase A2 Modification of Lipoproteins: Potential Effects on Atherogenesis". Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 5 . Advances in Experimental Medicine and Biology. Vol. 507. pp. 3– 7. doi :10.1007/978-1-4615-0193-0_1 . ISBN 978-1-4613-4960-0 PMID 12664556 . Murakami M, Kudo I (2004). "New phospholipase A(2) isozymes with a potential role in atherosclerosis". Curr. Opin. Lipidol . 14 (5): 431– 6. doi :10.1097/00041433-200310000-00003 . PMID 14501581 . S2CID 28202085 . Lennon G, Auffray C, Polymeropoulos M, Soares MB (1996). "The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression" . Genomics . 33 (1): 151– 2. doi :10.1006/geno.1996.0177 PMID 8617505 . Mavoungou E, Georges-Courbot MC, Poaty-Mavoungou V, et al. (1997). "HIV and SIV envelope glycoproteins induce phospholipase A2 activation in human and macaque lymphocytes" . J. Acquir. Immune Defic. Syndr. Hum. Retrovirol . 16 (1): 1– 9. doi :10.1097/00042560-199709010-00001 PMID 9377118 . Yokota Y, Higashino K, Nakano K, et al. (2000). "Identification of group X secretory phospholipase A(2) as a natural ligand for mouse phospholipase A(2) receptor" . FEBS Lett . 478 (1– 2): 187– 91. doi :10.1016/S0014-5793(00)01848-2 PMID 10922494 . S2CID 28188560 . Morioka Y, Saiga A, Yokota Y, et al. (2000). "Mouse group X secretory phospholipase A2 induces a potent release of arachidonic acid from spleen cells and acts as a ligand for the phospholipase A2 receptor". Arch. Biochem. Biophys . 381 (1): 31– 42. doi :10.1006/abbi.2000.1977 . PMID 11019817 . Degousee N, Ghomashchi F, Stefanski E, et al. (2002). "Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis" . J. Biol. Chem . 277 (7): 5061– 73. doi :10.1074/jbc.M109083200 PMID 11741884 . Hanasaki K, Yamada K, Yamamoto S, et al. (2002). "Potent modification of low density lipoprotein by group X secretory phospholipase A2 is linked to macrophage foam cell formation" . J. Biol. Chem . 277 (32): 29116– 24. doi :10.1074/jbc.M202867200 PMID 12021277 . Osterström A, Dimberg J, Fransén K, Söderkvist P (2002). "Expression of cytosolic and group X secretory phospholipase A(2) genes in human colorectal adenocarcinomas". Cancer Lett . 182 (2): 175– 82. doi :10.1016/S0304-3835(02)00081-2 . PMID 12048163 . Pan YH, Yu BZ, Singer AG, et al. (2002). "Crystal structure of human group X secreted phospholipase A2. Electrostatically neutral interfacial surface targets zwitterionic membranes" . J. Biol. Chem . 277 (32): 29086– 93. doi :10.1074/jbc.M202531200 PMID 12161451 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899– 903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Wooton-Kee CR, Boyanovsky BB, Nasser MS, et al. (2004). "Group V sPLA2 hydrolysis of low-density lipoprotein results in spontaneous particle aggregation and promotes macrophage foam cell formation" . Arterioscler. Thromb. Vasc. Biol . 24 (4): 762– 7. CiteSeerX 10.1.1.496.1425 doi :10.1161/01.ATV.0000122363.02961.c1 PMID 14962950 . Mounier CM, Ghomashchi F, Lindsay MR, et al. (2004). "Arachidonic acid release from mammalian cells transfected with human groups IIA and X secreted phospholipase A(2) occurs predominantly during the secretory process and with the involvement of cytosolic phospholipase A(2)-alpha" (PDF) . J. Biol. Chem . 279 (24): 25024– 38. doi :10.1074/jbc.M313019200 PMID 15007070 . S2CID 19214808 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121– 7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Masuda S, Murakami M, Takanezawa Y, et al. (2005). "Neuronal expression and neuritogenic action of group X secreted phospholipase A2" . J. Biol. Chem . 280 (24): 23203– 14. doi :10.1074/jbc.M500985200 PMID 15781456 .
PDB gallery
1le6 : CARBOXYLIC ESTER HYDROLASE, P 1 21 1 SPACE GROUP
1le7 : CARBOXYLIC ESTER HYDROLASE, C 2 2 21 space group
