Megasphaera

Megasphaera
Scientific classification
Domain:	Bacteria
Phylum:	Bacillota
Class:	Negativicutes
Order:	Veillonellales
Family:	Veillonellaceae
Genus:	Megasphaera; Rogosa 1971
Type species
	Megasphaera elsdenii; (Gutierrez et al. 1959) Rogosa 1971
Species
	See text

Megasphaera is a genus of Bacillota bacteria classified within the class Negativicutes.^[1]^[2]

This classification has been reexamined.^[3] This genus appears to be a member of the Clostridia.

Phylogeny

16S rRNA based LTP_10_2024^[4]^[5]^[6]

120 marker proteins based GTDB 09-RS220^[7]^[8]^[9]

Megasphaera

M. micronuciformis Marchandin et al. 2003

Anaeroglobus geminatus Carlier et al. 2002

	M. paucivorans Juvonen and Suihko 2006

	M. sueciensis Juvonen and Suihko 2006

	M. cerevisiae Engelmann and Weiss 1986

	M. vaginalis Srinivasan et al. 2021 non Bordigoni et al. 2020

	M. hutchinsoni Srinivasan et al. 2021

	M. lornae Srinivasan et al. 2021

M. massiliensis Padmanabhan et al. 2016

	M. elsdenii (Gutierrez et al. 1959) Rogosa 1971

	M. indica Lanjekar et al. 2014

Megasphaera_C

"Caecibacter"

	"Megasphaera hominis"

	"C. massiliensis" Ricaboni et al. 2017 (incl. Megasphaera hexanoica)

Megasphaera paucivorans

Anaeroglobus

Megasphaera vaginalis Bordigoni et al. 2020 non Srinivasan et al. 2021

"Colibacter massiliensis" Mailhe et al. 2017

Megasphaera

M. cerevisiae

M. stantonii

Unassigned species:

^ ^a ^b ^c A.C. Parte; et al. "Megasphaera". List of Prokaryotic names with Standing in Nomenclature (LPSN). Retrieved 2025-02-28.
^ ^a ^b C.L. Schoch; et al. "Megasphaera". National Center for Biotechnology Information (NCBI) taxonomy database. Retrieved 2025-02-28.
^ Yutin N, Galperin MY (2013) A genomic update on Clostridial phylogeny: Gram-negative spore formers and other misplaced Clostridia. Environ Microbiol doi: 10.1111/1462-2920.12173
^ "The LTP". Retrieved 10 December 2024.
^ "LTP_all tree in newick format". Retrieved 10 December 2024.
^ "LTP_10_2024 Release Notes" (PDF). Retrieved 10 December 2024.
^ "GTDB release 09-RS220". Genome Taxonomy Database. Retrieved 10 May 2024.
^ "bac120_r220.sp_labels". Genome Taxonomy Database. Retrieved 10 May 2024.
^ "Taxon History". Genome Taxonomy Database. Retrieved 10 May 2024.

Arik, H. D., Gulsen, N., Hayirli, A., & Alatas, M. S. (2019). Efficacy of Megasphaera elsdenii inoculation in subacute ruminal acidosis in cattle. Journal of animal physiology and animal nutrition, 103(2), 416–426.

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