Protein-coding gene in humans
Neuronal membrane glycoprotein M6-b is a protein that in humans is encoded by the GPM6B gene .[ 5] [ 6]
In melanocytic cells, GPM6B gene expression may be regulated by MITF .[ 7]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000046653 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031342 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Olinsky S, Loop BT, DeKosky A, Ripepi B, Weng W, Cummins J, Wenger SL, Yan Y, Lagenaur C, Narayanan V (Sep 1996). "Chromosomal mapping of the human M6 genes". Genomics . 33 (3): 532– 6. doi :10.1006/geno.1996.0231 . PMID 8661015 . ^ "Entrez Gene: GPM6B glycoprotein M6B" .^ Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy" . Pigment Cell Melanoma Res . 21 (6): 665– 76. doi :10.1111/j.1755-148X.2008.00505.x PMID 19067971 .
Further reading
Yan Y, Lagenaur C, Narayanan V (1993). "Molecular cloning of M6: identification of a PLP/DM20 gene family". Neuron . 11 (3): 423– 31. doi :10.1016/0896-6273(93)90147-J . PMID 8398137 . S2CID 46719251 . Narayanan V, Olinsky S, Dahle E, et al. (1998). "Mutation analysis of the M6b gene in patients with Rett syndrome". Am. J. Med. Genet . 78 (2): 165– 8. doi :10.1002/(SICI)1096-8628(19980630)78:2<165::AID-AJMG13>3.0.CO;2-L . PMID 9674909 . Yoshida M, Shan WS, Colman DR (1999). "Conserved and divergent expression patterns of the proteolipid protein gene family in the amphibian central nervous system". J. Neurosci. Res . 57 (1): 13– 22. doi :10.1002/(SICI)1097-4547(19990701)57:1<13::AID-JNR2>3.0.CO;2-E . PMID 10397631 . S2CID 28005024 . Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination" . Genome Res . 10 (11): 1788– 95. doi :10.1101/gr.143000 . PMC 310948 PMID 11076863 . Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs" . Genome Res . 11 (3): 422– 35. doi :10.1101/gr.GR1547R . PMC 311072 PMID 11230166 . Werner H, Dimou L, Klugmann M, et al. (2002). "Multiple splice isoforms of proteolipid M6B in neurons and oligodendrocytes". Mol. Cell. Neurosci . 18 (6): 593– 605. doi :10.1006/mcne.2001.1044 . PMID 11749036 . S2CID 24468488 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899– 903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40– 5. doi :10.1038/ng1285 PMID 14702039 . Henneke M, Wehner LE, Hennies HC, et al. (2005). "Mutation analysis of the M6b gene in patients with Pelizaeus-Merzbacher-like syndrome". Am. J. Med. Genet. A . 128 (2): 156– 8. doi :10.1002/ajmg.a.30068 . PMID 15214007 . S2CID 83895622 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121– 7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline" . Genome Res . 14 (10B): 2136– 44. doi :10.1101/gr.2576704 . PMC 528930 PMID 15489336 . Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006" . Nucleic Acids Res . 34 (Database issue): D415–8. doi :10.1093/nar/gkj139 . PMC 1347501 PMID 16381901 .
