CLaCS (Cryo-Laser and Cryo-Sclerotherapy) is a treatment for leg vein lesions by combining transdermal laser effect and injection sclerotherapy, all under skin cooling (Cryo - cold air blown onto the skin at -20C).[1][2][3] The laser causes a selective photothermolysis damaging the vein wall. The vein's lumen gets smaller. On a second procedure, sclerosing agent is injected where the vein is still open. This combination can be used treat veins that could be treated by phleboectomy or foam sclerotherapy - more invasive options. To improve results, CLaCS can be guided by Augmented Reality[4] (near-infrared vein finder).[5]
CLaCS was created by Dr. Roberto Kasuo Miyake (also knowns as Kasuo Miyake), in 1999, to adhere to patients' requests for treatment that did not require hospitalizations.[3]
^Miyake, RK; Zeman, HD; Duarte, FH; Kikuchi, R; Ramacciotti, E; Lovhoiden, G; Vrancken, C (2014-01-24). "Vein imaging: a new method of near infrared imaging, where a processed image is projected onto the skin for the enhancement of vein treatment". Dermatol Surg. 32 (8): 1031–8. doi:10.1111/j.1524-4725.2006.32226.x. PMID16918565. S2CID8872471.