January 20 – Inauguration of Joe Biden as the 46th president of the United States amid tight security in the aftermath of the January 6 attack on the Capitol.
The GameStop short squeeze reaches its peak of $483 per share, as the result of influence from the online community, r/wallstreetbets, drawing international attention.[18]
COVID-19 pandemic: A joint WHO–China investigation into the source of the outbreak concludes. Investigators deem a Wuhan laboratory leak to be "extremely unlikely", with a "natural reservoir" in bats being a more likely origin.[28]
The UAE's uncrewed Hope spacecraft becomes the first Arabian mission successfully to enter orbit around Mars.[29]
February 24 – COVID-19 pandemic: the COVAX vaccine-sharing initiative delivers its first vaccines, delivering 600,000 doses for healthcare workers in Ghana.[36]
North Koreasevers diplomatic ties with Malaysia due to a Malaysian court's ruling that a North Korean citizen could be extradited to the United States to face money-laundering charges. Malaysian authorities order North Korean officials to leave the country in 48 hours.[43]
Ever Given, one of the largest container ships in the world, runs aground and obstructs the Suez Canal, disrupting global trade.[49] The ship is freed on March 29.[50]
March 25 – COVID-19 pandemic: The number of vaccinations administered worldwide exceeds 500 million.[51]
Iran accuses Israel of "nuclear terrorism" and vows revenge after a large explosion destroys the internal power system of the Natanz uranium enrichment plant.[58]
Twelve football clubs, including three from La Liga and leading clubs from the Premier League and Serie A, agree to join a new breakaway European Super League, prompting international condemnation.[65] Two days later, following major protests from supporters, other clubs and politicians, Manchester City withdraw from the league; this prompts all the remaining Premier League clubs and three others to do the same.[66]
UEFA announces that due to a lack of guarantees regarding spectators caused by the COVID-19 pandemic, Aviva Stadium in Dublin, Ireland would be removed as a tournament host for the UEFA Euro 2020.[74]
Following an international search and rescue effort, the Indonesian navy reports the sinking of KRI Nanggala with 53 crew members, the largest loss of life aboard a submarine since 2003.[75]
COVID-19 pandemic: The number of vaccinations administered worldwide exceeds 1 billion. Half of these doses have been administered in just three countries (the United States, China and India).[76]
May 15 – Fighting between Israeli forces and Palestinian militants continues to escalate, as the death toll exceeds 150. An Israeli airstrike destroys a high-rise office building in Gaza occupied by Associated Press, Al Jazeera, and other media outlets.[92]
May 20 – Following international pressure, and nearly 250 deaths, Israel agrees to a ceasefire deal to end the conflict with Gaza militants, effective the next day at 2:00 am local time.[97]
July 12 – 2021 European floods: Heavy rain causes flooding in the border region of Germany and Belgium, resulting in 229 deaths, including 184 in Germany, 42 in Belgium with 1 person still missing there,[152] and 2 in Romania.[153] The event is attributed to a slowed jetstream caused by climate change.[152]
Roscosmos' Nauka laboratory docks with the International Space Station following a protracted seventeen-year development and launch on 21 July. Hours after docking, a malfunction of its thrusters causes a temporary loss of control of the station, spinning it up to 45 degrees from its normal orbital attitude.[166]
August 14 – A 7.2-magnitude earthquake strikes Haiti, killing more than 2,500 people.[179]UK coalition forces assist a child during an evacuation at Hamid Karzai International Airport, Kabul
August 27 – The United States launches an airstrike that it claims killed the Islamic State member who was believed to have planned the Kabul airport bombings.[184] However, the U.S. Defense Department later acknowledged that the strike instead killed ten civilians, including seven children, and that no terrorists were killed.[185]
North Korea demonstrates two short-range ballistic missiles that land just outside Japan's territorial waters; and then only hours later South Korea demonstrates its first submarine-launched ballistic missile.[195]
AUKUS: A trilateral security pact between Australia, the United Kingdom, and the United States is formed, to counter the influence of China. This includes enabling Australia to build its first nuclear-powered submarine fleet.[197]
Several ministers of the Argentine president Alberto Fernández's cabinet resign after the government's defeat in the primary elections, triggering a political crisis in the country.[198][199]
October 23 – Colombia's most wanted drug lord, Dario Antonio Úsuga, whose Gulf Clan controls many smuggling routes into the US and other countries, is captured by Colombia's armed forces.[223][224]